Journal article
Characterization of a sequence of human T cell leukemia virus type I from a patient with chronic progressive myelopathy
The Journal of infectious diseases, v 158(6), pp 1193-1197
Dec 1988
PMID: 3198935
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
DNA from peripheral blood mononuclear cells of individuals with chronic progressive myelopathy (CPM) were extensively analyzed for the presence of human T cell leukemia virus (HTLV) type I-like sequences by using the polymerase chain reaction. The DNA samples were amplified with oligonucleotides from three separate regions of HTLV viral genomes. A portion of the amplified viral genome from a representative patient was sequenced after molecular cloning into bacteriophage M13. Sequence data indicate that HTLV type I and not a related virus is associated with CPM.
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Details
- Title
- Characterization of a sequence of human T cell leukemia virus type I from a patient with chronic progressive myelopathy
- Creators
- S Kwok - Cetus CorporationD KelloggG EhrlichB PoieszS BhagavatiJ J Sninsky
- Publication Details
- The Journal of infectious diseases, v 158(6), pp 1193-1197
- Publisher
- Oxford University Press
- Grant note
- CA-37478 / NCI NIH HHS NALB1-HB-86-09 / NHLBI NIH HHS
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Microbiology and Immunology
- Web of Science ID
- WOS:A1988R227100006
- Scopus ID
- 2-s2.0-0024269043
- Other Identifier
- 991019196531904721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Immunology
- Infectious Diseases
- Microbiology