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Characterization of major depression symptoms in multiple sclerosis patients
Journal article   Peer reviewed

Characterization of major depression symptoms in multiple sclerosis patients

T F Scott, D Allen, T R Price, H McConnell and D Lang
The journal of neuropsychiatry and clinical neurosciences, v 8(3), pp 318-323
01 Jan 1996
PMID: 8854304

Abstract

Retrospective review of affective disturbances in 238 patients with multiple sclerosis (MS) seen over a 6-month period revealed: 1) 51 patients (22%) received pharmacologic treatment for depressive symptoms during or within 4 years of the study period, and 17 (7%) received treatment for rapid mood swings; 2) among the 51 depressed patients, response rate to medication was extremely high; 3) relapse of depressive symptomatology after discontinuation of medication was also high (17/29); 4) first episodes of major depression frequently occurred during periods of MS progression or exacerbation, but first episodes also occurred during periods of relative clinical stability; 5) suicidal ideation was common (12 patients), but only 1 patient had a history of attempted suicide; and 6) side effects were tolerable in most patients.

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Collaboration types
Domestic collaboration
Web of Science research areas
Clinical Neurology
Neurosciences
Psychiatry
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