Journal article
Childhood Hib vaccination and pneumonia and influenza burden in US seniors
Vaccine, v 28(28), pp 4462-4469
2010
PMID: 20457288
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
This analysis examines the potential for the elderly to receive indirect protection from pneumonia and influenza (P&I) from vaccination of children. Using data from the Centers for Medicare and Medicaid Services, the National Immunization Survey, and the Behavioral Risk Factor Surveillance System, mixed-effects models were used to assess associations between vaccination coverage and P&I on the state level overall and by urbanicity and income. As vaccination coverage in children increased, the state-level P&I rates in seniors decreased (
β
=
−0.040, −0.074 to 0.006), where
β represents the expected change in the logged age-associated rate of disease increase for a one-percentage point increase in vaccination coverage. Increasing vaccination coverage in the elderly was associated with an increase in P&I rates (
β
=
0.045, 0.011–0.077) in seniors. The degree of association was more prominent in urban and high income areas. The consistent associations between influenza in the elderly and vaccination coverage in children suggest that routine vaccination of children may impart some indirect protection to the elderly.
Metrics
Details
- Title
- Childhood Hib vaccination and pneumonia and influenza burden in US seniors
- Creators
- Steven A Cohen - Department of Population, Family and Reproductive Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USASaifuddin Ahmed - Department of Population, Family and Reproductive Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USAAnn C Klassen - Department of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USAEmily M Agree - Department of Population, Family and Reproductive Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USAThomas A Louis - Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USAElena N Naumova - Department of Public Health and Community Medicine, Tufts School of Medicine, Boston, MA, USA
- Publication Details
- Vaccine, v 28(28), pp 4462-4469
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Community Health and Prevention
- Web of Science ID
- WOS:000279490400005
- Scopus ID
- 2-s2.0-77953023539
- Other Identifier
- 991014877750904721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Immunology
- Medicine, Research & Experimental