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Childhood Lyme arthritis: Experience in an endemic area
Journal article   Peer reviewed

Childhood Lyme arthritis: Experience in an endemic area

Andrew H. Eichenfield, Donald P. Goldsmith, Jorge L. Benach, Avron H. Ross, Franklin X. Loeb, Robert A. Doughty and Balu H. Athreya
The Journal of pediatrics, v 109(5), pp 753-758
01 Nov 1986
DOI: https://doi.org/10.1016/S0022-3476(86)80688-6
PMID: 3772655
Featured in Collection :   UN Sustainable Development Goals @ Drexel

Abstract

We report 25 children with oligoarticular arthritis associated with Lyme disease. There were 16 boys (male/female ratio 1.8:1); ages ranged from 2 to 15 years. Thirteen (52%) children had no history of erythema chronicum migrans or other rash. Thirteen had temperatures as high as 41° C for up to 2 months before the onset of arthritis. Twelve recalled definite tick bites. Ten (40%) children, of whom seven had no history of rash, were hospitalized for presumed septic arthritis. Another four had diagnoses of pauciarticular juvenile rheumatoid arthritis for as long as 3 years. Seven patients had less acute, recurrent episodes of synovitis. Two children had seventh nerve palsies 2 months before onset of arthritis. All patients had antibodies to the Lyme spirochete. In 14 patients, synovial fluid white blood cell counts ranged from 180 to 97,700/mm 3 (≥76% polymorphonuclear leukocytes). Antibiotic therapy was effective in all patients; in 13, orally administered therapy alone resulted in elimination of synovitis and recurrent attacks. Lyme arthritis may be confused with acute bacterial septic arthritis or recurrent “pauciarticular juvenile rheumatoid arthritis,” particularly when there is no history of erythema chronicum migrans.

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Collaboration types
Domestic collaboration
Web of Science research areas
Pediatrics
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