Journal article
Chronic Spinal Cord Injury in the Pediatric Population Does Magnetic Resonance Imaging Correlate With the International Standards for Neurological Classification of Spinal Cord Injury Examination?
Spine (Philadelphia, Pa. 1976), v 34(1), pp 74-81
01 Jan 2009
PMID: 19127164
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Abstract
Study Design. Prognostic, retrospective case series.
Objective. This study is part of a larger investigation to develop and validate a standardized and reliable method to evaluate and classify the neurologic consequence of spinal cord injury (SCI) in children. Such an instrument may also find use in the evaluation of patients with concomitant brain injury and/or cognitive impairment. We examined the relationship between the International Standards for Neurologic Classification of Spinal Cord Injury (ISCSCI) examination and magnetic resonance imaging (MRI) findings in a pediatric SCI population.
Summary of Background Data. Recently, the reliability of the ISCSCI in young children with SCI who are unable to cognitively engage in the examination has been called into question. This has important implications as appropriate classification of these patients is necessary for prognostication, follow-up care, and appropriate placement into clinical trials.
Methods. Our longitudinal pediatric SCI database was reviewed for children with chronic SCI (> 6 months), ISCSCI examinations performed by experienced testers, and adequate MRIs of the spine. ISCSCI results were correlated with MRI findings. Twenty-six subjects were identified.
Results. Overall, good to excellent relationships between ISCSCI neurologic level (NL) and MRI level of injury were found [Kendall tau correlation coefficient 0.90 (P < 0.001)]. The ISCSCI NL was on an average, two-thirds of a vertebral level cephalad to the center of the lesion on MRI. One child with MRI evidence of cord disruption tested incomplete at ISCSCI examination.
Conclusion. The ISCSCI examination was found to have good to excellent relationships with MRI level in children with chronic SCI. Our results suggest MRI may be a useful adjunct for the determination of NL in children unable to participate with the examination. Our results also suggest caution in using the ISCSCI for the determination of completeness in young children. Further research into new methods ( e. g., diffusion tensor imaging) to determine completeness of injury is warranted.
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Details
- Title
- Chronic Spinal Cord Injury in the Pediatric Population Does Magnetic Resonance Imaging Correlate With the International Standards for Neurological Classification of Spinal Cord Injury Examination?
- Creators
- Amer F. Samdani - Shriners Hospitals for Children, 3551 North Broad Street, Philadelphia, PA 19140, USAReginald S. Fayssoux - Drexel Univ, Coll Med, Philadelphia, PA 19104 USAJahangir Asghar - Shriners Hosp Children, Philadelphia, PA 19140 USAJames J. McCarthy - Univ Wisconsin Hosp & Clin, Madison, WI 53792 USARandal R. Betz - Shriners Hosp Children, Philadelphia, PA 19140 USAJohn Gaughan - Temple Univ, Sch Med, Philadelphia, PA 19122 USAMary Jane Mulcahey - Shriners Hosp Children, Philadelphia, PA 19140 USA
- Publication Details
- Spine (Philadelphia, Pa. 1976), v 34(1), pp 74-81
- Publisher
- Lippincott Williams & Wilkins
- Number of pages
- 8
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Surgery
- Web of Science ID
- WOS:000263261000013
- Scopus ID
- 2-s2.0-61749091261
- Other Identifier
- 991019167752804721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Clinical Neurology
- Orthopedics