Journal article
Chronic surgical site infection due to suture-associated polymicrobial biofilm
Surgical infections, v 10(5), pp 457-461
Oct 2009
PMID: 19811056
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Surgical site infection (SSI) is a common surgical complication; culture-negative SSI presents a particular problem in management.
Examination of explanted foreign bodies (sutures) using confocal laser scanning microscopy (CLSM) and fluorescent in situ hybridization (FISH) after surgical exploration of a chronic culture-negative SSI.
Confocal microscopy (CM) demonstrated bacilli and cocci attached to the surface of the explanted sutures in a mixed biofilm. Fluorescent in situ hybridization confirmed that Staphylococci were components of the mixed biofilm. Removal of the foreign bodies (sutures) resolved the chronic infection.
Chronic SSI can arise from underlying bacterial biofilms, which can invest implanted foreign bodies and associated soft tissue surfaces.
Metrics
Details
- Title
- Chronic surgical site infection due to suture-associated polymicrobial biofilm
- Creators
- Sandeep Kathju - Center for Genomic Sciences, Allegheny-Singer Research Institute, Allegheny General Hospital, Pittsburgh, Pennsylvania 15212, USA. skathju@wpahs.orgLaura NisticoLuanne Hall-StoodleyJ Christopher PostGarth D EhrlichPaul Stoodley
- Publication Details
- Surgical infections, v 10(5), pp 457-461
- Publisher
- Mary Ann Liebert; United States
- Grant note
- DC04173 / NIDCD NIH HHS DE014780 / NIDCR NIH HHS
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Microbiology and Immunology
- Web of Science ID
- WOS:000279012700013
- Scopus ID
- 2-s2.0-72449122343
- Other Identifier
- 991014877877504721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Infectious Diseases
- Surgery