Journal article
Circadian rhythm in atopic dermatitisPathophysiology and implications for chronotherapy
Pediatric dermatology, v 35(1), pp 152-157
01 Jan 2018
PMID: 29231268
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Circadian rhythm is a biological clock that controls a wide range of physiological functions throughout the body, including various skin functions. A 24-h diurnal cycle, governed by an endogenous clock in the brain, largely controls cutaneous diurnal rhythm, which external factors, including temperature, humidity, diet, and stress, also modulate locally. Circadian rhythm influences cutaneous blood flow and properties of skin barrier function, such as transepidermal water loss and capacitance, and has important implications in atopic dermatitis (AD). This review explores how aberrations in circadian rhythm may play a role in the pathogenesis of AD and proposes implementation of chronotherapy to improve treatment outcomes in patients with AD.
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Details
- Title
- Circadian rhythm in atopic dermatitisPathophysiology and implications for chronotherapy
- Creators
- Alexandra R. Vaughn - Drexel UniversityAshley K. Clark - University of California, DavisRaja K. Sivamani - California State University, SacramentoVivian Y. Shi - University of Arizona
- Publication Details
- Pediatric dermatology, v 35(1), pp 152-157
- Publisher
- Wiley
- Number of pages
- 6
- Grant note
- Novartis
- Resource Type
- Journal article
- Language
- English
- Web of Science ID
- WOS:000423038100061
- Scopus ID
- 2-s2.0-85040815998
- Other Identifier
- 991019357769704721
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InCites Highlights
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Dermatology
- Pediatrics