Click chemistry on azidoproline: high-affinity dual antagonist for HIV-1 envelope glycoprotein gp120

Journal article

Peer reviewed

Hosahudya N Gopi, Kalyan C Tirupula, Sabine Baxter, Sandya Ajith and Irwin M Chaiken

ChemMedChem, v 1(1)

Jan 2006

PMID: 16892335

Additional Links

Anti-HIV Agents - pharmacology

Amino Acid Sequence

Proline - analogs & derivatives

Molecular Sequence Data

HIV Envelope Protein gp120 - drug effects

Structure-Activity Relationship

Azides - chemistry

HIV Envelope Protein gp120 - metabolism

Proline - chemistry

Anti-HIV Agents - chemistry

Proline - pharmacology

Protein Binding

Azides - pharmacology

HIV Envelope Protein gp120 - chemistry

CD4 Antigens - metabolism

10 Record Views

55 citations in Scopus

Title: Click chemistry on azidoproline: high-affinity dual antagonist for HIV-1 envelope glycoprotein gp120
Creators: Hosahudya N Gopi - Department of Biochemistry and Molecular Biology and A. J. Drexel Institute of Basic and Applied Protein Science, 11102 New College Building, Drexel University College of Medicine, 245 N. 15th Street, Philadelphia, PA 19102, USA
Kalyan C Tirupula
Sabine Baxter
Sandya Ajith
Irwin M Chaiken
Publication Details: ChemMedChem, v 1(1)
Publisher: Wiley; Germany
Grant note: P01 GM 056550-08/C21 / NIGMS NIH HHS
Resource Type: Journal article
Language: English
Academic Unit: Biochemistry and Molecular Biology
Web of Science ID: WOS:000202945500008
Scopus ID: 2-s2.0-33746272623
Other Identifier: 991014878228604721

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Web of Science research areas: Chemistry, Medicinal; Pharmacology & Pharmacy