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Published, Version of Record (VoR) Open Access via Drexel Libraries Read and Publish Program 2026 Open CC BY V4.0
Journal article
Clinical and Demographic Predictors of Peptic Esophageal Stricture in a National Cohort of Patients with GERD
Journal of gastrointestinal surgery, Forthcoming
16 Jun 2026
PMID: 42303115
Featured in Collection : Research Supported by Drexel Libraries' OA Programs
Abstract
Since the introduction of proton pump inhibitors (PPIs), the incidence of peptic esophageal stricture has declined, yet a subset of patients with gastroesophageal reflux disease (GERD) continue to develop this complication. Peptic stricture is associated with dysphagia, recurrent endoscopic intervention, and substantial healthcare utilization, making it a clinically meaningful outcome of reflux disease. Contemporary data defining its incidence, risk factors, and clinical sequelae remain limited. In this multicenter national database study, we evaluated the incidence of peptic esophageal stricture among patients with GERD, characterized the population that develops stricture, identified predictors of stricture formation, and assessed associated clinical sequelae.
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Details
- Title
- Clinical and Demographic Predictors of Peptic Esophageal Stricture in a National Cohort of Patients with GERD
- Creators
- Sven E Eriksson - Allegheny Health NetworkHimsikhar Khataniar - Allegheny Health NetworkPing Zheng - Allegheny Health NetworkShahin Ayazi (Corresponding Author) - Drexel University, Surgery
- Publication Details
- Journal of gastrointestinal surgery, Forthcoming
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Surgery
- Other Identifier
- 991022189368904721