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Clinical and demographic features of infection caused by Acinetobacter species
Journal article   Peer reviewed

Clinical and demographic features of infection caused by Acinetobacter species

Suresh G Joshi, Geetanjali M Litake, Meenakshi G Satpute, Nilima V Telang, Vikram S Ghole and Krishna B Niphadkar
Indian journal of medical sciences, v 60(9), pp 351-360
01 Sep 2006
DOI: https://doi.org/10.4103/0019-5359.27219
PMID: 16940684

Abstract

BACKGROUNDRecently, Acinetobacter emerged as an important pathogen and the prevalence of isolation has increased since the last two decades worldwide. AIMSTo determine Acinetobacter incidence, their clinical demography, antibiotyping and speciation. SETTINGS AND DESIGNA study of the clinical samples submitted to microbiology laboratory of a teaching hospital over a period of 3 years (December 1994 through November 1997). MATERIALS AND METHODSIdentification, speciation and antibiotyping were performed for the isolates of Acinetobacter recovered from infective samples. Clinical demographic characteristics were studied retrospectively. RESULTSTotal 510 of 5391 (9.6%) of isolates were Acinetobacter, responsible for 71.2% (363 of 510) monomicrobial and 28.8% (147 of 510) polymicrobial infections. The organism was responsible for 156 (30.6%) cases of urinary tract infection and 140 (27.5%) cases of wound infection and was most prevalent in the intensive care unit (30.8%, 140 of 455). The crude mortality rate due to multi-drug resistant Acinetobacter septicemia was 7.9% (36 of 455). The isolates could be classified into 7 species, with A. baumannii being most predominant. No peculiar pattern during antibiotyping was observed, but most of them were multi-drug resistant. CONCLUSIONMulti-drug resistant Acinetobacter nosocomial infection has emerged as an increasing problem in intensive care units of the hospital, responsible for 7.9% deaths. The analysis of risk factors and susceptibility pattern will be useful in understanding epidemiology of this organism in a hospital setup.

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