Journal article
Clinical characteristics and outcomes of patients with right congenital diaphragmatic hernia: A population-based study
Journal of pediatric surgery, v 50(5), pp 731-733
01 May 2015
PMID: 25783377
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Purpose: The purpose of this study was to compare RCDH to LCDH from the perspective of prenatal diagnosis, illness severity, treatment, and outcome.
Methods: A retrospective study of all cases of CDH registered in the Canadian Pediatric Surgery Network (CAPSNet) database from 2005 to 2013 was conducted. Side of defect comparisons were made by prenatal diagnostic features, birth demographic data, intensity of medical treatment, timing and type of surgery, and outcomes. Outcomes predictionwith logistic regression modeling using side of defect as an exploratory covariate was performed.
Results: The study cohort included 498 patients, of which 84 (17%) cases had RCDH. Prenatal diagnosiswas more commonly made for LCDH. No difference existed in perinatal risk factors (GA, illness severity (SNAP-II) score, associated anomalies), preoperative treatment intensity (use of vasodilators, inotropes), timing of surgery, ventilation days, need for ECMO, LOS, and overall survival. Significant differences between RCDH and LCDH were detected for patch repair rate (48.2% vs. 30.6%; p = 0.036) and recurrence (4.1% vs. 0.6%; p = 0.038). Stepwise regression modeling identified side of hernia as independently predictive of need for patch.
Conclusions: Overall, little difference exists between RCDHand LCDHin terms of prognostic factors and outcomes. (C) 2015 Elsevier Inc. All rights reserved.
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Details
- Title
- Clinical characteristics and outcomes of patients with right congenital diaphragmatic hernia: A population-based study
- Creators
- Catherine K. Beaumier - University of British ColumbiaAlana L. Beres - McGill UniversityPramod S. Puligandla - McGill UniversityErik D. Skarsgard - University of British ColumbiaCanadian Pediat Surg Network
- Publication Details
- Journal of pediatric surgery, v 50(5), pp 731-733
- Publisher
- Elsevier
- Number of pages
- 3
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Surgery
- Web of Science ID
- WOS:000353813300006
- Scopus ID
- 2-s2.0-84928698816
- Other Identifier
- 991021969586504721
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InCites Highlights
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Pediatrics
- Surgery