Journal article
Clonal chromosome rearrangements in a uterine myoma
Cancer genetics and cytogenetics, v 32(1)
1988
PMID: 3355997
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
A cytogenetic study of a myoma of uterus with extensive hyaline, myxoid, and cystic degeneration revealed a clonal karyotype with a complex structural rearrangement involving chromosomes #3, #12, #14, #17, and #22. The modal chromosome number of the tumor was 45 due to monosomy #22. Analysis of seven additional myomas of the uterus including five tumors with typical histology and two with degenerative changes showed no clonal abnormalities. Single metaphases with a trisomy and a translocation were detected in two tumors. We conclude that although many uterine myomas appear to have normal karyotypes, clonal chromosome abnormalities are present in some of these tumors.
Metrics
Details
- Title
- Clonal chromosome rearrangements in a uterine myoma
- Creators
- Z. Gibas - Drexel UniversityC.A. Griffin - Pediatrics and GeneticsB.S. Emanuel - Pediatrics and Genetics
- Publication Details
- Cancer genetics and cytogenetics, v 32(1)
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Accelerated Career Entry Bachelor of Science in Nursing (BSN)
- Web of Science ID
- WOS:A1988N155800004
- Scopus ID
- 2-s2.0-0023922998
- Other Identifier
- 991019184293104721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Genetics & Heredity
- Oncology