Journal article
Coencapsulation of lipid microbubbles within polymer microcapsules for contrast applications
Bubble science engineering and technology, v 3(1), pp 12-19
01 May 2011
Abstract
In this work, the authors examine the acoustic response generated by the coencapsulation of phospholipid shelled microbubbles within the aqueous core of polymer microcapsules and its feasibility as an ultrasound contrast agent. The addition of the polymer shell provides the added benefit of approximately doubling the inertial cavitation threshold of the microbubbles contained within. The feasibility of the utilisation of the coencapsulated contrast agent as a drug delivery vehicle is also discussed. It is concluded that the coencapsulated contrast agent provides contrast similar to that of unencapsulated microbubbles, both in acoustic response and image intensity of contrast to tissue.
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10 citations in Scopus
Details
- Title
- Coencapsulation of lipid microbubbles within polymer microcapsules for contrast applications
- Creators
- S Dicker - Drexel UniversityM Mleczko - Ruhr University BochumK Hensel - Ruhr University BochumA Bartolomeo - Drexel UniversityG Schmitz - Ruhr University BochumS P Wrenn - Drexel University
- Publication Details
- Bubble science engineering and technology, v 3(1), pp 12-19
- Publisher
- Routledge
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Chemical and Biological Engineering
- Scopus ID
- 2-s2.0-79957638478
- Other Identifier
- 991019174892404721