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Color- Doppler- Directed Echocardiographie T echnique for the Evaluation of Left Ventricular Diastolic Filling: Validation by Radionuclide Angiography
Journal article   Peer reviewed

Color- Doppler- Directed Echocardiographie T echnique for the Evaluation of Left Ventricular Diastolic Filling: Validation by Radionuclide Angiography

Jian-Fang Ren, Mark Tulchinsky, Krishnaswamy Chandrasekaran, John J Ross Jr, Robert V Foley, Dean G Karalis, Ronald S Pennock and William S Frankl
American journal of noninvasive cardiology, v 7(1), pp 1-6
1993

Abstract

Original Paper
A novel color-Doppler-directed échocardiographie technique was developed for the determination of left ventricular (LY) peak filling rate normalized to the end-diastolic volume (NPFR). To calculate this diastolic filling index, the mitral valve cross-sectional area (MVA) was measured using color Doppler inflow column width for guidance, and the LY volumes were determined by biplane Simpson’s rule. For comparison, NPFR was measured in a similar fashion by a non-color Doppler échocardiographie (DE) technique with MVA determined on the gray scale image. Radionuclide angiography (RNA) was used as a reference standard. Thirty-two patients were considered for this study. Seven were excluded because of technical (5 cases) or pathophysiological reasons. The mean NPFR values for color DE, non-color DE and RNA were 2.14 ± 1.03, 2.83 ± 1.43 and 2.08 ± 1.43 s_1, respectively. There was a fair correlation demonstrated between the non-color DE method and RNA (r = 0.60, SEE = 1.18 s_1). On the other hand, an excellent correlation existed between the color DE method and RNA (r = 0.85, SEE = 0.55 s-1). This improvement was statistically significant (p < 0.05). In conclusion, the color DE method for determination of NPFR is more reliable than the non-color DE method in reproducing RNA results. However, DE techniques are considerably less applicable than RNA, because 22% of the patients successfully tested with RNA could not be studied with DE methods.

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