Journal article
Combined Treatment for Obesity and Depression: A Pilot Study
Obesity (Silver Spring, Md.), v 26(7), pp 1144-1152
Jul 2018
PMID: 29932516
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Obesity and depression frequently co-occur, and each increases risk for cardiovascular disease (CVD). This study tested whether a combined treatment, targeting obesity and depression simultaneously, would yield greater improvements in weight, mood, and CVD risk factors than treatments that targeted each disease individually.
Seventy-six participants with obesity and major depression were randomly assigned to (1) behavioral weight control (BWC), (2) cognitive behavioral therapy for depression (CBT-D), or (3) BWC combined with CBT-D. Participants were provided 18 group treatment sessions over 20 weeks. Mood, weight, and CVD risk were assessed at baseline and weeks 8 and 20, with a follow-up visit at week 46.
At week 20, participants in combined treatment lost significantly (P < 0.02) more weight (5.2% ± 1.2%) than those assigned to CBT-D (0.8% ± 1.3%) and comparable amounts as those in BWC (3.5% ± 1.3%). Depression scores decreased significantly from baseline levels in each group, with no significant differences between groups. All three groups showed significant improvements in 10-year CVD risk, with no significant differences between groups. Groups did not differ significantly on any of these measures at week 46.
BWC yielded short-term improvements in weight, mood, and CVD risk, comparable to a combined treatment that incorporated CBT-D. Results require replication with a larger sample size.
Metrics
Details
- Title
- Combined Treatment for Obesity and Depression: A Pilot Study
- Creators
- Lucy F Faulconbridge - University of PennsylvaniaColleen F B Driscoll - University of PennsylvaniaChristina M Hopkins - University of PennsylvaniaBrooke Bailer Benforado - University of PennsylvaniaChanelle Bishop-Gilyard - University of PennsylvaniaRaymond Carvajal - University of PennsylvaniaRobert I Berkowitz - University of PennsylvaniaRobert DeRubeis - University of PennsylvaniaThomas A Wadden - University of Pennsylvania
- Publication Details
- Obesity (Silver Spring, Md.), v 26(7), pp 1144-1152
- Publisher
- Wiley
- Grant note
- K23 HL109235 / NHLBI NIH HHS
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Center for Weight, Eating and Lifestyle Science (WELL) [Historical]
- Web of Science ID
- WOS:000435949600009
- Scopus ID
- 2-s2.0-85048853621
- Other Identifier
- 991022016373104721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Endocrinology & Metabolism
- Nutrition & Dietetics