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Comparative clinical evaluation of mezlocillin and cefoxitin
Journal article   Peer reviewed

Comparative clinical evaluation of mezlocillin and cefoxitin

J. L. LeFrock, A. Molavi, B. Carr, R. Schell, B. Smith, K. Rolston and A. Lentnek
Journal of antimicrobial chemotherapy, v 9(suppl-A)
1982
PMID: 6210667

Abstract

The efficacy and toxicity of cefoxitin and mezlocillin were compared in a clinical study. In 41 patients treated with cefoxitin and 39 treated with mezlocillin, the clinical response was favourable in 89.5% and 94.1% respectively. Both antibiotics were effective in the treatment of septicaemia, pulmonary infection, urinary tract infection, intra-abdominal and pelvic infections, and skin and soft-tissue infections. They were equally effective in the treatment of infections caused by anaerobic organisms. No major haematologic, hepatic, or renal toxicity was encountered in patients treated with either drug.

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Web of Science research areas
Infectious Diseases
Microbiology
Pharmacology & Pharmacy
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