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Comparative prostate MRI before and after chronic granulomatous prostatitis following intravesical bacillus Calmette-Guerin therapy
Journal article   Open access   Peer reviewed

Comparative prostate MRI before and after chronic granulomatous prostatitis following intravesical bacillus Calmette-Guerin therapy

Julien Sarkis, Georges Nawfal, Elias El-Haddad, Georges Abi Tayeh, Nathalie Mahfoud and Pierre Sarkis
Future science OA, v 7(2), pFSO637
01 Sep 2020
PMID: 33437511
url
https://doi.org/10.2144/fsoa-2020-0065View
Published, Version of Record (VoR) Open

Abstract

Life Sciences & Biomedicine Medicine, Research & Experimental Research & Experimental Medicine Science & Technology
Background: Granulomatous prostatitis (GnP) is an interesting complication of bacillus Calmette-Guerin (BCG) therapy as it mimics prostate cancer on clinical, biochemical and imaging examinations. In the era of multiparametric prostate MRI (mpMRI), differentiation of GnP from prostate cancer on imaging is essential. Case presentation: We report a case of post-BCG GnP in a patient with nonmuscle invasive bladder cancer, presenting with a prostate-specific antigen level of 21.6 ng/ml and prostate imaging reporting and data system (PI-RADS) 5 peripheral lesions. A mpMRI performed 6 months before showed a score 2 of PI-RADS. Conclusion: The comparison of mpMRI images before and after BCG administration gives urologists, oncologists and radiologists a precise idea of the mpMRI changes that occur following BCG administration to eventually prevent unnecessary biopsies in future patients.

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