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Comparison between continuous non-invasive estimated cardiac output by pulse wave transit time and thermodilution method
Journal article   Open access   Peer reviewed

Comparison between continuous non-invasive estimated cardiac output by pulse wave transit time and thermodilution method

Ashish C Sinha, Preet Mohinder Singh, Navneet Grewal, Mansoor Aman and Gerald Dubowitz
Annals of cardiac anaesthesia, v 17(4)
Oct 2014
DOI: https://doi.org/10.4103/0971-9784.142059
PMID: 25281622
Featured in Collection :   UN Sustainable Development Goals @ Drexel
url
https://doi.org/10.4103/0971-9784.142059View
Published, Version of Record (VoR)CC BY-NC-SA V4.0,  Open

Abstract

Adult Aged Aged, 80 and over Cardiac Output - physiology Catheterization, Swan-Ganz - methods Female Humans Male Middle Aged Monitoring, Intraoperative - methods Monitoring, Intraoperative - statistics & numerical data Monitoring, Physiologic - methods Monitoring, Physiologic - statistics & numerical data Prospective Studies Pulse Wave Analysis - methods Pulse Wave Analysis - statistics & numerical data Reproducibility of Results Thermodilution - methods Thermodilution - statistics & numerical data Young Adult
Cardiac output (CO) measurement is essential for many therapeutic decisions in anesthesia and critical care. Most available non-invasive CO measuring methods have an invasive component. We investigate "pulse wave transit time" (estimated continuous cardiac output [esCCO]) a method of CO measurement that has no invasive component to its use. After institutional ethical committee approval, 14 adult (21-85 years) patients undergoing surgery and requiring pulmonary artery catheter (PAC) for measuring CO, were included. Postoperatively CO readings were taken simultaneously with thermodilution (TD) via PAC and esCCO, whenever a change in CO was expected due to therapeutic interventions. Both monitoring methods were continued until patients' discharge from the Intensive Care Unit and observer recording values using TD method was blinded to values measured by esCCO system. Three hundred and one readings were obtained simultaneously from both methods. Correlation and concordance between the two methods was derived using Bland-Altman analysis. Measured values showed significant correlation between esCCO and TD ( r = 0.6, P < 0.001, 95% confidence limits of 0.51-0.68). Mean and (standard deviation) for bias and precision were 0.13 (2.27) L/min and 6.56 (2.19) L/min, respectively. The 95% confidence interval for bias was - 4.32 to 4.58 L/min and for precision 2.27 to10.85 L/min. Although, esCCO is the only true non-invasive continuous CO monitor available and even though its values change proportionately to TD method (gold standard) with the present degree of error its utility for clinical/therapeutic decision-making is questionable.

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11 citations in Web of Science
13 citations in Scopus

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Collaboration types
Domestic collaboration
International collaboration
Web of Science research areas
Anesthesiology
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