Journal article
Comparison of Bacterial and Fungal Adherence to Vaginal Exfoliated Epithelial Cells and Human Vaginal Epithelial Tissue Culture Cells
Infection and immunity, v 35(2), pp 697-701
01 Jan 1982
PMID: 6120141
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The adherence of four bacterial species and Candida albicans to a new in vitro tissue culture model of human vaginal stratified squamous epithelium was investigated and compared with in vitro adherence to vaginal exfoliated cells. Gardnerella vaginalis , group B streptococci, Lactobacillus sp., and C. albicans adhered well to both exfoliated and tissue culture cells. Similarly, a piliated fecal isolate of Escherichia coli , but not a nonpiliated vaginal isolate of E. coli , adhered well to both cell types. Adherence of the piliated E. coli was markedly inhibited by preincubation of bacteria with D-mannose. No inhibition of adherence by D-mannose of G. vaginalis , nonpiliated E. coli , and C. albicans was demonstrated. Scanning electron microscopy of tissue cultures showed nonuniform distribution of adherent microorganisms with diminished adherence in areas of active mitosis and proliferation and increased adherence to mature flat cells, often in the process of desquamation.
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Details
- Title
- Comparison of Bacterial and Fungal Adherence to Vaginal Exfoliated Epithelial Cells and Human Vaginal Epithelial Tissue Culture Cells
- Creators
- M E LevisonJ SobelP MyersD Kaye
- Publication Details
- Infection and immunity, v 35(2), pp 697-701
- Publisher
- American Society for Microbiology (ASM)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Medicine (Graduate)
- Web of Science ID
- WOS:A1982MZ50200048
- Scopus ID
- 2-s2.0-0020056437
- Other Identifier
- 991019183921904721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Immunology
- Infectious Diseases