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Comparison of Locoregional Recurrence with Mastectomy vs. Breast Conserving Surgery in Pregnancy Associated Breast Cancer (PABC)
Journal article   Open access   Peer reviewed

Comparison of Locoregional Recurrence with Mastectomy vs. Breast Conserving Surgery in Pregnancy Associated Breast Cancer (PABC)

Sushil Beriwal, Bunja Rungruang, Atilla Soran, Darcy Thull, Joseph L. Kelley, Rohit Bhargava, Chyongchiou J. Lin and Paniti Sukumvanich
Cancers, v 1(1), pp 12-20
04 Dec 2009
DOI: https://doi.org/10.3390/cancers1010012
PMID: 24280969
url
https://doi.org/10.3390/cancers1010012View
Published, Version of Record (VoR) Open

Abstract

We have compared outcomes, including the locoregional recurrence, between mastectomy and breast conserving therapy in PABC. Patients were divided into those who were treated with mastectomies (group 1) and those with breast conserving surgery (group 2). The groups were comparable except for lower mean age in group 2 and more patients with stage III disease and higher number of nodes positive in the group 1. Five-year actuarial LRR, distant metastases free survival and overall survival in group 1 vs. 2 were 10% vs. 37%, 73% vs. 81% and 57% vs. 59% respectively. The patients with PABC treated with breast conserving therapy, despite having lower stage disease, have a higher risk of local regional recurrence in comparison with those treated with mastectomy.

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