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Journal article
Comparison of antigenic heterogeneity of Neisseria gonorrhoeae strains by micro-immunofluorescence and serum bactericidal tests
Infection and immunity, v 22(2), pp 403-410
Nov 1978
PMCID: PMC422170
PMID: 83299
Abstract
The antigenic heterogeneity of Neisseria gonorrhoeae strains was assessed by the micro-immunofluorescence (micro-IF) and the serum bactericidal tests. The micro-IF test verified the antigenic heterogeneity of nine strains received from the Center for Disease Control and placed them into immunotypes A and B. The serum bactericidal system also detected different antigenic determinants among the strains. Although the micro-IF and bactericidal assays did not correspond in each instance, the overall pattern of similarities and differences among these gonococcal strains was similar. The micro-IF pattern obtained with mouse antisera was identical to the pattern revealed with guinea pig antisera. Different colony type organisms showed similar sensitivity in the bactericidal test. The micro-IF test is a rapid technique for the immunotyping of N. gonorrhoeae and has the additional advantages of reproducibility and simplicity.
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Details
- Title
- Comparison of antigenic heterogeneity of Neisseria gonorrhoeae strains by micro-immunofluorescence and serum bactericidal tests
- Creators
- J A MarkS P Wang
- Publication Details
- Infection and immunity, v 22(2), pp 403-410
- Publisher
- American Society for Microbiology (ASM)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- School of Biomedical Engineering, Science, and Health Systems; Drexel University
- Web of Science ID
- WOS:A1978FW26100018
- Scopus ID
- 2-s2.0-0018079161
- Other Identifier
- 991019350296504721