Journal article
Comparison of self-expanding and balloon-expandable stents for the reduction of restenosis
The American journal of cardiology, v 88(3), pp 253-259
01 Aug 2001
PMID: 11472703
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
To compare the efficacy of self-expanding (SE) and balloon-expandable (BE) stents in native coronary arteries, we randomly assigned 1,096 patients with new and restenotic lesions to receive either device. Baseline demographics and coronary angiographic characteristics were similar in the 2 groups. The incidence of major adverse cardiac events including death, myocardial infarction, bypass surgery, and repeat intervention was similar for both groups at 1 month (2.9% vs 3.1% for SE vs BE, respectively) and at 9 months (19.3% vs 20.1%, SE vs BE respectively). In a subgroup of patients who underwent follow-up angiography (n = 250), the binary restenosis rates (24.2% vs 18.7%, p = 0.30), late loss (0.98 vs 94 mm, p = 0.60), and loss index (0.55 vs 55, p = 0.95) were not significantly different for both groups. In 62 patients who underwent intravascular ultrasound examination (IVUS), there was a trend toward a lower incidence of edge tears in the SE group (6% vs 23%, p = 0.06). Follow-up IVUS analysis showed that the minimum stent area of the SE stent increased by 33% at 6 months, whereas no change occurred in the BE stents; this was accompanied by a greater degree of intimal proliferation in the SE stents compared with BE stents (3.1 ± 2.0 vs 1.7 ± 1.7 mm2). Thus, the SE stents had similar clinical and angiographic outcomes in patients with lesions in native coronary arteries.
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Details
- Title
- Comparison of self-expanding and balloon-expandable stents for the reduction of restenosis
- Creators
- Richard O. Han - Massachusetts General HospitalRobert S. Schwartz - Mayo Clinic,Rochester,Minnesota,USAYoshiki Kobayashi - Stanford UniversityStephanie H. Wilson - Mayo Clinic,Rochester,Minnesota,USAJ.Tift Mann - Wake ResearchMichael H. Sketch - Duke UniversityRobert D. Safian - William Beaumont HospitalAlexandra Lansky - MedStar Washington Hospital CenterJeffrey Popma - Brigham and Women's HospitalPeter J. Fitzgerald - Stanford UniversityIgor F. Palacios - Massachusetts General HospitalMarilyn Chazin-Caldie - Boston ScientificSheldon Goldberg - Cooper University Hospitalfor the Stent COmparative REStenosis (SCORES) Trial Investigators
- Publication Details
- The American journal of cardiology, v 88(3), pp 253-259
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Medicine (Graduate)
- Web of Science ID
- WOS:000170090500010
- Scopus ID
- 2-s2.0-0035421786
- Other Identifier
- 991019167529104721
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- Collaboration types
- Industry collaboration
- Domestic collaboration
- Web of Science research areas
- Cardiac & Cardiovascular Systems