Journal article
Complications of intracavitary brachytherapy for gynecologic cancers and their management: A comprehensive review
Brachytherapy, v 20(5), pp 984-994
01 Sep 2021
PMID: 33478905
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Intracavitary gynecologic brachytherapy in the form of tandem-based brachytherapy and vaginal cylinder-based brachytherapy represents a fundamental component of the treatment of women with cervical or uterine cancer due to the ability to deliver a therapeutic dose of radiation with sharp dose falloff. This results in highly effective treatment in terms of oncologic outcomes with an overall favorable toxicity profile. Still, complications and side effects of brachytherapy do exist. While advances in brachytherapy techniques have led to a significant decrease in the rates of toxicity, a thorough understanding of the potential complications is crucial to ensuring optimal outcomes for women with gynecologic cancer undergoing brachytherapy. Use of equivalent dose at 2 Gy per fraction (EQD2) models has allowed incorporation of external beam radiotherapy dose to the brachytherapy dose leading to development of consolidated dose constraints for organs-at-risk in the modern era. This manuscript offers a comprehensive review of potential complications associated with intracavitary brachytherapy for gynecologic cancer including predictive factors, mitigation tactics, and management strategies. (C) 2020 American Brachytherapy Society. Published by Elsevier Inc. All rights reserved.
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Details
- Title
- Complications of intracavitary brachytherapy for gynecologic cancers and their management: A comprehensive review
- Creators
- Scott M. Glaser - City Of Hope National Medical CenterPranshu Mohindra - College Station Medical CenterUmesh Mahantshetty - Mécanique et Engrenage ModerneSushil Beriwal - UPMC Hillman Canc Ctr, Dept Radiat Oncol, Pittsburgh, PA USA
- Publication Details
- Brachytherapy, v 20(5), pp 984-994
- Publisher
- Elsevier
- Number of pages
- 11
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Radiation Oncology (and Nuclear Medicine)
- Web of Science ID
- WOS:000707062000002
- Scopus ID
- 2-s2.0-85099618364
- Other Identifier
- 991021897375604721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Oncology
- Radiology, Nuclear Medicine & Medical Imaging