Journal article
Comprehensive Cost Implications of Commercially Available Noninvasive Colorectal Cancer Screening Modalities
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, v 237(3), p465
Sep 2023
PMID: 37219020
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
BACKGROUND: There is an increasing usage of noninvasive screening modalities for colorectal cancer (CRC), primarily the fecal immunochemical test (FIT) and multi-target stool DNA test (Cologuard [CG]). The aim of this study was to determine the comprehensive, long-term cost implications of these noninvasive screening modalities. STUDY DESIGN: Using a national insurer-based administrative dataset, patients screened for CRC from January 1, 2019 to December 31, 2019 were analyzed. A hierarchical logic system was used to determine the primary screening modality for each patient. The total annual costs in US dollars ($) were extrapolated using number of patients screened, costs per test, screening intervals, and costs incurred from false results. Patients within our tumor registry diagnosed with CRC were matched to their claims data, and cancer stage distribution was compared. RESULTS: Of 119,334 members who underwent noninvasive screening, 38.1% underwent screening with FIT and 40.0% with CG. The combined annual cost for these 2 screening modalities was $13.7 million. By transitioning to FIT alone for all noninvasive screening, the total annual cost would decrease to $7.9 million, resulting in a savings of approximately $5.8 million per year. Additionally, by combining data from the network cancer registry and insurer-based claims dataset, we were able to match 533 individuals who underwent screening and were later diagnosed with CRC. The rate of early-stage (stage 0 to II) disease was found to be similar between those screened with FIT and CG (59.5% FIT vs 63.2% CG; p = 0.77). CONCLUSIONS: The adoption of FIT as the primary noninvasive CRC screening method has the potential to generate significant cost savings, and therefore, carries significant value implications for a large population health system. (c) 2023 by the American College of Surgeons. Published by Wolters Kluwer Health, Inc. All rights reserved.)
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Details
- Title
- Comprehensive Cost Implications of Commercially Available Noninvasive Colorectal Cancer Screening Modalities
- Publication Details
- JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, v 237(3), p465
- Publisher
- LIPPINCOTT WILLIAMS & WILKINS; PHILADELPHIA
- Grant note
- The authors thank Sarah Carey, MS, Jade Chang, and Jacalyn Newman, PhD, of Allegheny Health Network's Health System Publication Support Office for their assistance in editing and formatting the manuscript. The Health Network's Health System Publication Support Office is funded by Highmark Health (Pittsburgh, PA) and all work was done in accordance with Good Publication Practice guidelines (http://www.ismpp.org/gpp3).
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Drexel University
- Web of Science ID
- WOS:001049960200012
- Scopus ID
- 2-s2.0-85168050147
- Other Identifier
- 991021861313104721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Surgery