Journal article
Computer-aided characterization for effective mechanical properties of porous tissue scaffolds
Computer aided design, v 37(1)
01 Jan 2005
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Performance of various functions of the tissue structure depends on porous scaffold microstructures with specific porosity characteristics that influence the behavior of the incorporated or ingrown cells. Understanding the mechanical properties of porous tissue scaffold is important for its biological and biomechanical tissue engineering application. This paper presents a computer aided characterization approach to evaluate the effective mechanical properties of porous tissue scaffold. An outline of a computer-aided tissue engineering approach for design and fabrication of porous tissue scaffold, procedure of computer-aided characterization and its interface with design model. development of a computational algorithm for finite element implementation and numerical solution of asymptotic homogenization theory is presented. Application of the algorithm to characterize the effective mechanical properties of porous poly-epsilon-caprolactone scaffold manufactured by precision extruding freeform deposition will also be presented, along with a parametric study of the process and design parameter to the structural properties of tissue scaffold. (C) 2004 Elsevier Ltd. All rights reserved.
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Details
- Title
- Computer-aided characterization for effective mechanical properties of porous tissue scaffolds
- Creators
- Z Fang - Drexel UniversityB Starly - Drexel UniversityW Sun - Drexel University
- Publication Details
- Computer aided design, v 37(1)
- Publisher
- Elsevier
- Number of pages
- 8
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Mechanical Engineering and Mechanics
- Web of Science ID
- WOS:000225426800006
- Scopus ID
- 2-s2.0-4544231126
- Other Identifier
- 991019167548904721
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- Web of Science research areas
- Computer Science, Software Engineering