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Computer-aided tissue engineering: overview, scope and challenges
Journal article   Peer reviewed

Computer-aided tissue engineering: overview, scope and challenges

Wei Sun, Andrew Darling, Binil Starly and Jae Nam
Biotechnology and applied biochemistry, v 39(Pt 1), pp 29-47
Feb 2004
PMID: 14563211

Abstract

Animals Artificial Organs Biocompatible Materials - chemical synthesis Blood Vessels - physiology Computer-Aided Design Humans Micromanipulation Models, Biological Tissue Engineering - methods Tissue Transplantation - methods
Advances in computer-aided technology and its application with biology, engineering and information science to tissue engineering have evolved a new field of computer-aided tissue engineering (CATE). This emerging field encompasses computer-aided design (CAD), image processing, manufacturing and solid free-form fabrication (SFF) for modelling, designing, simulation and manufacturing of biological tissue and organ substitutes. The present Review describes some salient advances in this field, particularly in computer-aided tissue modeling, computer-aided tissue informatics and computer-aided tissue scaffold design and fabrication. Methodologies of development of CATE modelling from high-resolution non-invasive imaging and image-based three-dimensional reconstruction, and various reconstructive techniques for CAD-based tissue modelling generation will be described. The latest development in SFF to tissue engineering and a framework of bio-blueprint modelling for three-dimensional cell and organ printing will also be introduced.

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Web of Science research areas
Biochemistry & Molecular Biology
Biotechnology & Applied Microbiology
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