Journal article
Convergence Insufficiency Neuro-mechanism in Adult Population Study Randomized Clinical Trial: Clinical Outcome Results
Optometry and vision science, v 97(12), pp 1061-1069
01 Dec 2020
PMID: 33186192
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
SIGNIFICANCE
These data confirm the effectiveness of office-based vergence/accommodative therapy for improving the near point of convergence and positive fusional vergence in young adults with symptomatic convergence insufficiency within a double-masked longitudinal randomized clinical trial. PURPOSE
This study aimed to report changes in clinical signs and symptoms of convergence insufficiency from a randomized clinical trial evaluating the effectiveness of office-based vergence/accommodative therapy for young adults with symptomatic convergence insufficiency. METHODS
In this double-masked, randomized clinical trial, convergence insufficiency patients (n = 50; average age, 21 +/- 3 years; range, 18 to 32 years) were randomized to either office-based vergence/accommodative therapy or office-based placebo therapy. Improvements in (1) near point of convergence, (2) positive fusional vergence, and (3) self-reported symptoms (Convergence Insufficiency Symptom Survey [CISS] score) were evaluated after twelve 1-hour sessions of treatment within the office comparing the results from the vergence/accommodative therapy and the placebo therapy groups. RESULTS
The mean near point of convergence improved by 6.0 and 3.1 cm in the vergence/accommodative and placebo therapy groups, respectively (mean difference of -2.9 cm; 95% confidence interval [CI], -4.6 to -1.0 cm; P < .01). The mean positive fusional vergence increased by 17.3 and 7.4 Delta in the vergence/accommodative and placebo therapy groups, respectively (mean difference of 9.9 Delta; 95% CI, 4.9 to 16.0 Delta; P < .001). The mean CISS score improved by 12.4 and 10.1 points in the vergence/accommodative and placebo therapy groups, respectively (mean difference of 2.3 points; 95% CI, -8.3 to +4.6 points; P = .56). CONCLUSIONS
Our results demonstrate that office-based vergence/accommodative therapy is effective for improving the near point of convergence and positive fusional vergence in young adults with symptomatic convergence insufficiency. However, given that both treatment groups had a similar reduction in self-reported symptoms, we recommend that the CISS be revised if it is to be used as an outcome measure in future studies of convergence insufficiency.
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Details
- Title
- Convergence Insufficiency Neuro-mechanism in Adult Population Study Randomized Clinical Trial: Clinical Outcome Results
- Creators
- Tara L. Alvarez - New Jersey Institute of TechnologyMitchell Scheiman - Salus UniversityElio M. Santos - New Jersey Institute of TechnologyChang Yaramothu - New Jersey Institute of TechnologyJohn Vito D'Antonio-Bertagnolli - New Jersey Institute of Technology
- Publication Details
- Optometry and vision science, v 97(12), pp 1061-1069
- Publisher
- Lippincott Williams & Wilkins
- Number of pages
- 9
- Grant note
- R01EY023261 / National Eye Institute; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Eye Institute (NEI)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Pennsylvania College of Optometry (PCO)
- Web of Science ID
- WOS:000598629500009
- Scopus ID
- 2-s2.0-85098603198
- Other Identifier
- 991021900612404721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Ophthalmology