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Conversion of enol trifluoromethanesulphonates into α,β-unsaturated nitriles
Journal article

Conversion of enol trifluoromethanesulphonates into α,β-unsaturated nitriles

Edward Piers and Fraser F Fleming
Journal of the Chemical Society, Chemical Communications, (12), pp 756-757
1989

Abstract

Reaction of enol trifluoromethanesulphonates with lithium cyanide in benzene (room temperature) in the presence of catalytic amounts of 12-crown-4 and tetrakis(triphenylphosphine)palladium(0) provides good to excellent yields of the corresponding α,β-unsaturated nitriles.

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