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Cornelia de Lange Syndrome: Otolaryngologic Manifestations
Journal article

Cornelia de Lange Syndrome: Otolaryngologic Manifestations

Robert Thayer Sataloff, Joseph R Spiegel, Mary Hawkshaw, Joanne M Epstein and Laird Jackson
Archives of otolaryngology--head & neck surgery, v 116(9), pp 1044-1046
01 Sep 1990
PMID: 2383389

Abstract

• Cornelia de Lange syndrome (CDLS) is characterized by multiple congenital malformations and mental retardation. New studies have documented otolaryngologic abnormalities. We examined 45 patients with CDLS. Virtually all had hearing loss, and most had impaired language development. Other otolaryngologic abnormalities, including external auditory canal stenosis and cleft palate, were also common. Because of the high incidence of otolaryngologic abnormalities, and the need for early intervention, it is important for otolaryngologists to recognize CDLS manifestations in the head and neck.(Arch Otolaryngol Head Neck Surg. 1990;116:1044-1046)

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Web of Science research areas
Otorhinolaryngology
Surgery
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