Journal article
Correlation between Presence of Viable Bacteria and Presence of Endotoxin in Middle-Ear Effusions
Journal of clinical microbiology, v 36(11), pp 3417-3419
Nov 1998
PMID: 9774611
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The presence of endotoxin (detected by the
Limulus
amebocyte lysate assay) was compared to the presence of viable
Haemophilus influenzae
and
Moraxella catarrhalis
(detected by PCR) in 106 middle-ear effusions from pediatric patients with chronic otitis media. Endotoxin was found in 81 of the 106 specimens. Of these 81 specimens, 66 (81.5%) also tested positive for one or both of the gram-negative bacteria
H. influenzae
and
M. catarrhalis
. The data suggest that viable gram-negative bacteria, detectable by PCR but often undetectable by culture, may be the source of endotoxin in middle-ear effusions.
Metrics
Details
- Title
- Correlation between Presence of Viable Bacteria and Presence of Endotoxin in Middle-Ear Effusions
- Creators
- Jeffrey R Dingman - Center for Genomic SciencesMark G Rayner - Center for Genomic SciencesSuman Mishra - Center for Genomic SciencesYingze Zhang - Center for Genomic SciencesMiles D Ehrlich - Center for Genomic SciencesJ. Christopher Post - Center for Genomic SciencesGarth D Ehrlich - Center for Genomic Sciences
- Publication Details
- Journal of clinical microbiology, v 36(11), pp 3417-3419
- Series
- Note
- Publisher
- American Society for Microbiology
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Microbiology and Immunology
- Web of Science ID
- WOS:000076491200063
- Scopus ID
- 2-s2.0-0031718332
- Other Identifier
- 991014970146604721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Microbiology