Journal article
Correlation of C3b-receptor activity and diphenylhexatriene polarization in a murine macrophage cell line
Biochemical and biophysical research communications, v 109(2), pp 328-333
1982
PMID: 6217816
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Treatment of a macrophage cell line with lymphokine (LK)-rich lymphocyte culture supernatants activates the cells for C3b receptor-mediated phagocytosis and leads to simultaneous depolarization of 1,6-diphenyl-1,3,5-hexatriene (DPH) incorporated into the cells. Maximal effects were observed after 14 hours of incubation with LK. DPH polarization in liposomes prepared from lipids of untreated and LK-treated cells were the same. Furthermore, LK-treatment had no significant effects on phospholipid fatty acid composition, cholesterol content, or phospholipid composition. These observations indicate LK induces alterations in the organization and dynamics of the plasma membrane that lead to facilitation of phagocytosis.
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Details
- Title
- Correlation of C3b-receptor activity and diphenylhexatriene polarization in a murine macrophage cell line
- Creators
- M. Esfahani - Hahnemann University HospitalP.H. Saluk - Hahnemann University HospitalD.R. Tabor - Hahnemann University HospitalL. Scerbo - Hahnemann University HospitalT.M. Devlin - Hahnemann University Hospital
- Publication Details
- Biochemical and biophysical research communications, v 109(2), pp 328-333
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Biochemistry and Molecular Biology; [Retired Faculty]
- Web of Science ID
- WOS:A1982PS01300005
- Scopus ID
- 2-s2.0-0020261523
- Other Identifier
- 991019183959304721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Biochemistry & Molecular Biology
- Biophysics