Journal article
Cortical transplants reveal CNS trophic interactions in situ
Brain research. Developmental brain research, v 15(2), pp 290-294
1984
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Five days after transplanting fetal rat posterior cortex into newborn host rats with posterior cortex lesions, the host's dorsal lateral geniculate nucleus (dLGN) contains 2–5 times as many neurons as the dLGN of lesion-only controls. This effect is temporary and restricted to neurons created later in dLGN neurogenesis. Similar transplants of cerebellar plate are ineffective. These findings suggest that intracranial transplants of CNS tissue can be a source of specific trophic support to particular host neurons.
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Details
- Title
- Cortical transplants reveal CNS trophic interactions in situ
- Creators
- Forrest Haun - Drexel UniversityTimothy J. Cunningham - Drexel University
- Publication Details
- Brain research. Developmental brain research, v 15(2), pp 290-294
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Neurobiology and Anatomy
- Web of Science ID
- WOS:A1984TK17300018
- Scopus ID
- 2-s2.0-0021473046
- Other Identifier
- 991019183977404721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Developmental Biology
- Neurosciences