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Cortico-thalamic interactions in response to whisker stimulation in a computer model of the rat barrel system
Journal article   Peer reviewed

Cortico-thalamic interactions in response to whisker stimulation in a computer model of the rat barrel system

K A Moxon and J K Chapin
Neurocomputing (Amsterdam), v 26-7, pp 809-822
01 Jun 1999

Abstract

Computer Science Computer Science, Artificial Intelligence Science & Technology Technology
Recent evidence from multi-unit recording experiments in awake rats has suggested that there may be complex, nonlinear interactions between the cortex and thalamus. In order to further study the possible role of the thalamus in cortical sensory processing, we have developed a computational model of the coritco-thalamic barrel region. In the model, single whisker stimulation can produce long latency responses in thalamic cells due to feedback from the cortex. Stimulus movement across the receptor surface, in the model, shows the ability of the thalamus to produce "priming" effects in the cortex or "memory" effects depending on the frequency of the stimulation. (C) 1999 Elsevier Science B.V. All rights reserved.

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