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Cost Effectiveness of Routine Gonadotropin and Androgen Measurements in Hirsute Women
Journal article   Peer reviewed

Cost Effectiveness of Routine Gonadotropin and Androgen Measurements in Hirsute Women

Elizabeth L. Helfer, Jeffrey L. Miller, Leslie I. Rose and Jacob L Miller
The American journal of the medical sciences, v 299(2), pp 94-97
Feb 1990
PMID: 2137289

Abstract

Androgens Gonadotropins Hirsutism Prolactin
Many physicians routinely measure the gonadotropins PRL, LH, and FSH and the androgens dehydroepiandrosterone (DHEA), dehydroepiandrosterone sulfate (DHEAS), an-drostenedione (ADIONE), and testosterone, as well as testosterone’s biologically active fractions in the evaluation of hirsute women. Is this cost effective? To answer this question, 38 consecutive premenopausal hirsute women were evaluated. Two women each had minor elevations in PRL and FSH, and 11 had minor elevations in LH. Three women had minor elevations in the LH/FSH ratio, and only one was above a ratio of 3, believed to be indicative of polycystic ovarian syndrome. Because these gonadotropin elevations did not correlate with the androgens measured and were of no value in the diagnosis or management of these women, they were not believed to be cost effective. Their routine measurements should be abandoned.

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Web of Science research areas
Endocrinology & Metabolism
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