Journal article
Cost-effectiveness of Inpatient Tympanostomy Prophylaxis
Otology & neurotology, v 42(10), pp 1521-1526
01 Dec 2021
PMID: 34420019
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Tympanostomy is the most common pediatric ambulatory surgery. Post-tympanostomy otorrhea is a prevalent complication leading to high costs to patients for treatment. The cost-effectiveness of intraoperative prophylaxis for both patient and institution has not been examined.
An analytical observational study of data collected from the literature and purchasing records.
A break-even analysis was performed to determine the required absolute risk reduction (ARR) and final infection rate in post-tympanostomy otorrhea to make intraoperative prophylaxis using ofloxacin and ciprofloxacin dexamethasone otic version cost effective with the following outpatient treatments: ofloxacin, ciprofloxacin-dexamethasone ophthalmic version, and ciprofloxacin-dexamethasone otic version. Absolute risk reduction is a statistic used to express the difference in risk between a treatment and control. The conservative initial infection rate used was 10%.
Ofloxacin intraoperative prophylaxis was not cost effective when prescribing ofloxacin outpatient treatment with an ARR of 0.20. Ofloxacin intraoperative prophylaxis was cost-effective with an ARR of 0.08 for ciprofloxacin-dexamethasone ophthalmic version outpatient treatment. Ofloxacin intraoperative prophylaxis was cost-effective for ciprofloxacin-dexamethasone otic version outpatient treatment with an ARR of 0.01.Ciprofloxacin-dexamethasone intraoperative prophylaxis was not cost-effective when prescribing ofloxacin outpatient treatment with an ARR of 1.52. Ciprofloxacin-dexamethasone intraoperative prophylaxis was not cost-effective when prescribing ciprofloxacin-dexamethasone ophthalmic version outpatient treatment with an ARR of 0.60. Ciprofloxacin-dexamethasone intraoperative prophylaxis was cost effective when prescribing ciprofloxacin-dexamethasone otic version outpatient treatment with an ARR of 0.09.
Intraoperative prophylaxis can be cost effective for preventing post-tympanostomy otorrhea. Physicians can use this economic model to determine the cost-effectiveness of these interventions for their patients and institutions.
Metrics
Details
- Title
- Cost-effectiveness of Inpatient Tympanostomy Prophylaxis
- Creators
- Heather Yeakel - University of MiamiLuke J Pasick - University of MiamiGregory J Kirchner - Penn State Milton S. Hershey Medical CenterBrian J McKinnon - The University of Texas Medical Branch at GalvestonRebecca C Chiffer - Thomas Jefferson University Hospital
- Publication Details
- Otology & neurotology, v 42(10), pp 1521-1526
- Publisher
- Lippincott
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Otolaryngology (and Head and Neck Surgery)
- Web of Science ID
- WOS:000717737500030
- Scopus ID
- 2-s2.0-85121958438
- Other Identifier
- 991019168425704721
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InCites Highlights
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Clinical Neurology
- Otorhinolaryngology