Journal article
Cost of Thoracotomy Approach: An Analysis of the LATERAL Trial
The Annals of thoracic surgery, v 110(5), pp 1512-1519
Nov 2020
PMID: 32224242
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Less invasive techniques for left ventricular assist device implantation have been increasingly prevalent over past years and have been associated with improved clinical outcomes. The procedural economic impact of these techniques remains unknown. We sought to study and report economic outcomes associated with the thoracotomy implantation approach.
The LATERAL clinical trial evaluated the safety and efficacy of the thoracotomy approach for implantation of the HeartWare centrifugal-flow ventricular assist device system (HVAD). We collected UB-04 forms in parallel to the trial, allowing analysis of index hospitalization costs. All charges were converted to costs using hospital-specific cost-to-charge ratios and were subsequently compared with Medicare cost data for the same period (2015-2016). Because thoracotomy implants were off-label for all left ventricular assist devices during that period, the Medicare cohort was assumed to consist predominately of traditional sternotomy patients.
Thoracotomy patients demonstrated decreased costs compared with sternotomy patients during the index hospitalization. Mean total index hospitalization costs for thoracotomy were $204,107 per patient, corresponding to 21.6% reduction (P < .001) and $56,385 savings per procedure compared with sternotomy. Across almost all cost categories, thoracotomy implants were less costly.
In LATERAL, a clinical trial evaluating the safety and efficacy of the thoracotomy approach for HVAD, costs were lower than those reported in Medicare patient claims occurring over the same period. Because Medicare data can be presumed to consist of predominately sternotomy procedures, thoracotomy appears less expensive than traditional sternotomy.
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Details
- Title
- Cost of Thoracotomy Approach: An Analysis of the LATERAL Trial
- Creators
- Nahush A Mokadam - The Ohio State University Wexner Medical CenterEdwin McGee, Jr - Loyola University Medical CenterGeorg Wieselthaler - University of California, San FranciscoDuc Thinh Pham - Northwestern UniversityStephen H Bailey - Allegheny General HospitalG Victor Pretorius - University of California, San DiegoTheodore J Boeve - Corewell Health Blodgett HospitalEleni Ismyrloglou - MedtronicMartin Strueber - Newark Beth Israel Medical Center
- Publication Details
- The Annals of thoracic surgery, v 110(5), pp 1512-1519
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Cardiothoracic Surgery
- Web of Science ID
- WOS:000580647400047
- Scopus ID
- 2-s2.0-85090300028
- Other Identifier
- 991021960654304721
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- Collaboration types
- Industry collaboration
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Cardiac & Cardiovascular Systems
- Respiratory System
- Surgery