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Cryptic community structure and metabolic interactions among the heritable facultative symbionts of the pea aphid
Journal article   Open access   Peer reviewed

Cryptic community structure and metabolic interactions among the heritable facultative symbionts of the pea aphid

Linyao Peng, Jessica Hoban, Jonah Joffe, Andrew H Smith, Melissa Carpenter, Tracy Marcelis, Vilas Patel, Nicole Lynn-Bell, Kerry M Oliver and Jacob A Russell
Journal of evolutionary biology
13 Sep 2023
url
https://doi.org/10.1111/jeb.14216View
Published, Version of Record (VoR)Maybe Open Access (Publisher Bronze) Open

Abstract

Most insects harbour influential, yet non-essential heritable microbes in their hemocoel. Communities of these symbionts exhibit low diversity. But their frequent multi-species nature raises intriguing questions on roles for symbiont–symbiont synergies in host adaptation, and on the stability of the symbiont communities, themselves. In this study, we build on knowledge of species-defined symbiont community structure across US populations of the pea aphid, Acyrthosiphon pisum. Through extensive symbiont genotyping, we show that pea aphids' microbiomes can be more precisely defined at the symbiont strain level, with strain variability shaping five out of nine previously reported co-infection trends. Field data provide a mixture of evidence for synergistic fitness effects and symbiont hitchhiking, revealing causes and consequences of these co-infection trends. To test whether within-host metabolic interactions predict common versus rare strain-defined communities, we leveraged the high relatedness of our dominant, community-defined symbiont strains vs. 12 pea aphid-derived Gammaproteobacteria with sequenced genomes. Genomic inference, using metabolic complementarity indices, revealed high potential for cooperation among one pair of symbionts—Serratia symbiotica and Rickettsiella viridis. Applying the expansion network algorithm, through additional use of pea aphid and obligate Buchnera symbiont genomes, Serratia and Rickettsiella emerged as the only symbiont community requiring both parties to expand holobiont metabolism. Through their joint expansion of the biotin biosynthesis pathway, these symbionts may span missing gaps, creating a multi-party mutualism within their nutrient-limited, phloem-feeding hosts. Recent, complementary gene inactivation, within the biotin pathways of Serratia and Rickettsiella, raises further questions on the origins of mutualisms and host–symbiont interdependencies.

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9 citations in Scopus

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Collaboration types
Domestic collaboration
Web of Science research areas
Ecology
Evolutionary Biology
Genetics & Heredity
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