Journal article
Cumulative Socioeconomic Status Across the Life Course and Subclinical Atherosclerosis
Annals of epidemiology, v 17(4), pp 296-303
01 Apr 2007
PMID: 17027292
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Abstract
Purpose: The purpose of this study is to investigate the relationship between individual-level and neighborhood-level socioeconomic status (SES) across the life course and subclinical atherosclerosis. Methods: Participants from the Atherosclerosis Risk in Communities Study (n = 12,332) were queried about individual-level SES and residential addresses across the life course. Individual-level measures were scored and summed to obtain a summary score (I-CumSES), whereas residential addresses were geocoded and linked to census data to obtain a summary neighborhood z score (N-CumSES) to evaluate the association of SES with intima-media thickness (IMT) and peripheral arterial disease (PAD). Results: A 1-SD lower I-CumSES was associated with greater mean IMT in each race-sex group and greater odds of PAD in white men (odds ratio [OR], 1.28; 95% confidence interval [CI], 0.99-1.64), white women (OR, 1.18; 95% CI, 1.02-1.36), and black women (OR, 1.33; 95% CI, 1.00-1.76). Compared with the highest tertile of N-CumSES, the lowest tertile was associated with greater mean IMT among whites, but was not associated with PAD for whites or blacks. When I-CumSES and N-CumSES were considered simultaneously, associations remained for only I-CumSES and were attenuated after adjustment for cardiovascular disease (CVD) risk factors. Conclusions: Lower cumulative individual-level SES across the life course was associated with a greater burden of subclinical atherosclerosis, and this association was mediated in part by CVD risk factors. © 2007 Elsevier Inc. All rights reserved.
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Details
- Title
- Cumulative Socioeconomic Status Across the Life Course and Subclinical Atherosclerosis
- Creators
- April P. Carson (Corresponding Author) - University of Mississippi Medical CenterKathryn M. Rose - University of North Carolina at Chapel HillDiane J. Catellier - Departments of Epidemiology and Biostatistics, School of Public Health, University of North Carolina at Chapel Hill, United StatesJay S. Kaufman - University of North Carolina at Chapel HillSharon B. Wyatt - University of Mississippi Medical CenterAna V. Diez-Roux - University of MichiganGerardo Heiss - University of North Carolina at Chapel Hill
- Publication Details
- Annals of epidemiology, v 17(4), pp 296-303
- Publisher
- Elsevier
- Number of pages
- 8
- Grant note
- R01HL064142 / National Heart, Lung, and Blood Institute (http://data.elsevier.com/vocabulary/SciValFunders/100000050) National Heart, Lung, and Blood Institute (http://data.elsevier.com/vocabulary/SciValFunders/100000050)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Urban Health Collaborative; Epidemiology and Biostatistics
- Web of Science ID
- WOS:000245685400008
- Scopus ID
- 2-s2.0-33947366857
- Other Identifier
- 991020112277004721
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- Collaboration types
- Industry collaboration
- Domestic collaboration
- Web of Science research areas
- Public, Environmental & Occupational Health