Journal article
Current Treatment Modalities for Spinal Metastases Secondary to Thyroid Carcinoma
Thyroid (New York, N.Y.), v 24(10), pp 1443-1455
01 Oct 2014
PMID: 24827757
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Background:
The spine is the most common site of bone metastases due to thyroid cancer, which develop in more than 3% of patients with well-differentiated thyroid cancer. Nearly half of patients with bone metastases from thyroid cancer develop vertebral metastases. Spinal metastases are associated with significantly reduced quality of life due to pain, neurological deficit, and increased mortality.
Summary:
Treatment options for patients with thyroid spinal metastases include radioiodine therapy, pharmacologic therapy, and surgical treatments, with recent advances in radiosurgery and minimally invasive spinal surgery as well. Therapeutic interventions require a multidisciplinary approach and aim to control pain, preserve or improve neurologic function, optimize local tumor control, and improve quality of life. We have proposed a three-tiered approach to the management and practical algorithms for patients with spinal metastases from thyroid carcinoma.
Conclusions:
The introduction of novel and improved techniques for the treatment of spinal metastases has created the opportunity to significantly improve control of metastatic tumor growth and the quality of life for the patients with spinal metastases from thyroid cancer. In order for these options to be effectively used, a multidisciplinary approach must be applied in the management of the patients with thyroid spinal metastases.
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Details
- Title
- Current Treatment Modalities for Spinal Metastases Secondary to Thyroid Carcinoma
- Creators
- Yevgeniya S. Kushchayeva - MedStar Washington Hospital CenterSergiy V. Kushchayev - Mercy Fitzgerald HospitalJason A. Wexler - MedStar Washington Hospital CenterNancy M. Carroll - MedStar Washington Hospital CenterMark C. Preul - St. Joseph's Hospital and Medical CenterOleg M. Teytelboym - Mercy Fitzgerald HospitalVolker K.H. Sonntag - St. Joseph's Hospital and Medical CenterDouglas Van Nostrand - MedStar Washington Hospital CenterKenneth D. Burman - MedStar Washington Hospital CenterLisa M. Boyle - MedStar Georgetown University Hospital
- Publication Details
- Thyroid (New York, N.Y.), v 24(10), pp 1443-1455
- Publisher
- Mary Ann Liebert, Inc
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Radiology (Radiologic Sciences); Medicine (Graduate)
- Web of Science ID
- WOS:000342742800003
- Scopus ID
- 2-s2.0-84911860556
- Other Identifier
- 991021897447804721
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InCites Highlights
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Endocrinology & Metabolism