Journal article
Current approaches to optimize the donor heart for transplantation
The Journal of heart and lung transplantation, v 44(4), pp 672-680
25 Dec 2024
PMID: 39730081
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Heart transplantation remains a critical therapy for patients with end-stage heart failure, offering incremental survival and improved quality of life. One of the key components behind the success of heart transplantation is the condition and preservation of the donor's heart. In this review, we provide a comprehensive overview of ischemic reperfusion injury, risk factors associated with primary graft dysfunction, current use of various preservation solutions for organ procurement, and recent advancements in donor heart procurement technologies. This state-of-the-art review will explore factors associated with bringing the “ideal” donor heart to the operating room in the contemporary era.
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Details
- Title
- Current approaches to optimize the donor heart for transplantation
- Creators
- Amit H. Alam - NYU Langone HealthCandice Y. Lee - Allegheny General HospitalManreet K. Kanwar - Drexel University, CardiologyYasbanoo Moayedi - University of TorontoAlexander M. Bernhardt - University Medical Center Hamburg-EppendorfKoji Takeda - Columbia UniversityDuc Thinh Pham - Northwestern UniversityChristopher Salerno - St Vincent HospitalAndreas Zuckermann - Medical University of ViennaDavid D’Alessandro - Massachusetts General HospitalVictor G. Pretorius - University of California, San DiegoJohn O. Louca - University of CambridgeStephen Large - Papworth HospitalDawn E. Bowles - Duke Medical CenterScott C. Silvestry - AdventHealth OrlandoNader Moazami - Cleveland Clinic
- Publication Details
- The Journal of heart and lung transplantation, v 44(4), pp 672-680
- Publisher
- Elsevier
- Number of pages
- 9
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Cardiology; Surgery
- Web of Science ID
- WOS:001450576200001
- Scopus ID
- 2-s2.0-85214310858
- Other Identifier
- 991022008092204721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Cardiac & Cardiovascular Systems
- Respiratory System
- Surgery
- Transplantation