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Cyclic Metalated Nitriles: Stereoselective Cyclizations to cis- and trans-Hydrindanes, Decalins, and Bicyclo[4.3.0]undecanes
Journal article   Open access   Peer reviewed

Cyclic Metalated Nitriles: Stereoselective Cyclizations to cis- and trans-Hydrindanes, Decalins, and Bicyclo[4.3.0]undecanes

Fraser F. Fleming and Subramanyham Gudipati
European journal of organic chemistry, v 2008(32), pp 5365-5374
01 Nov 2008
PMID: 24260015
url
https://europepmc.org/articles/pmc3831376View
Accepted (AM)Open Access (License Unspecified) Open

Abstract

Chemistry Chemistry, Organic Physical Sciences Science & Technology
Metalated nitriles are nucleophilic chameleons whose precise identity is determined by the nature of the metal, the solvent, the temperature, and the structure of the nitrile. The review surveys the different structural types and their cyclization trajectories to show how to selectively tune the metalated nitrile geometry for stereoselective cyclizations to a variety of cis or trans hydrindanes, decalins, and bicyclo[4.3.0]undecanes.( (C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)

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Industry collaboration
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Web of Science research areas
Chemistry, Organic
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