Journal article
Cytochrome levels and activity in stored human platelets
Archives of biochemistry and biophysics, v 215(2), pp 532-538
1982
PMID: 6284054
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Aspects of the cytochrome levels and function in stored human platelets were investigated. Platelets stored in a synthetic medium lose cytochrome
c very rapidly with virtually all of the cytochrome
c being lost by 3 days. Platelets aged in their homologous plasma, however, lose cytochrome
c more slowly with a half-life of 7.3 days which is assumed to be more closely related to the
in vivo situation. Cytochrome oxidase activity does not change in platelets stored up to 8 days in plasma. Oxygen consumption by platelets maintained
in vitro drops slowing during the first 4 days of storage, however, by the fifth and sixth day the oxygen consumption drops dramatically and is accompanied by a reduction in coupling. The observed changes in the cytochrome levels and respiration are discussed with regard to platelet function and survival.
Metrics
Details
- Title
- Cytochrome levels and activity in stored human platelets
- Creators
- Gerald Soslau - Department of Biochemistry and The H. L. Orlowitz Cancer Institute, Hahnemann Medical School, 230 N. Broad Street, Philadelphia, Pennsylvania 19102 U.S.A.
- Publication Details
- Archives of biochemistry and biophysics, v 215(2), pp 532-538
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- [Retired Faculty]
- Web of Science ID
- WOS:A1982NL69100018
- Scopus ID
- 2-s2.0-0020416250
- Other Identifier
- 991019184070004721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Biochemistry & Molecular Biology
- Biophysics