Journal article
DXA-derived abdominal fat-free mass to predict MRI skeletal muscle mass in postmenopausal women
Applied physiology, nutrition, and metabolism, v 49(11), pp 1606-1610
01 Nov 2024
PMID: 39079168
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Dual-energy X-ray absorptiometry (DXA) is more available than gold-standard magnetic resonance imaging (MRI), but DXA ability to estimate abdominal skeletal muscle mass (SMM) is unknown. DXA-derived abdominal fat-free mass (FFM; Hologic QDR2000 or QDR4500w) was correlated with single-slice MRI SMM at L4 (N = 69; r QDR2000 = 0.71, QDR4500w = 0.69; p < 0.0001). Linear regression to predict SMM, including DXA FFM, BMI, and age, resulted in an R-squared of 0.72 and 0.65 for QDR2000 and QDR4500. Bland-Altman limits of agreement were +/- 21 and +/- 31 g for 2-3 standard deviations from the mean difference. DXA predicted abdominal SSM is a moderate proxy for MRI abdominal SMM.
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Details
- Title
- DXA-derived abdominal fat-free mass to predict MRI skeletal muscle mass in postmenopausal women
- Creators
- E. Walker - University of ArizonaA. M. Chalke - University of ArizonaV. L. Bland - University of ArizonaK. E. Lind - University of ArizonaZ. Chen - University of ArizonaR. M. Blew - University of ArizonaA. O. Odegaard - University of California, IrvineC. A. Thomson - University of ArizonaB. Caan - Kaiser PermanenteJ. S. Nicholas - University of ArizonaC. Valencia - University of ArizonaD. J. Roe - University of ArizonaM. Allison - California Department of Public HealthP. F. Schnatz - Drexel UniversityJ. Wactawski-Wende - University at Buffalo, State University of New YorkJ. W. Bea - University of Arizona
- Publication Details
- Applied physiology, nutrition, and metabolism, v 49(11), pp 1606-1610
- Publisher
- Canadian Science Publishing
- Number of pages
- 5
- Grant note
- R01CA253302 / National Cancer Institute; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Cancer Institute (NCI) R01AG055018 / National Institute on Aging; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute on Aging (NIA) 75N92021D00001; 75N92021D00002; 75N92021D00003; 75N92021D00004; 75N92021D00005 / National Heart, Lung, and Blood Institute, National Institutes of Health, U.S. Department of Health and Human Services; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Heart Lung & Blood Institute (NHLBI)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- School of Biomedical Engineering and Science
- Web of Science ID
- WOS:001366326900006
- Other Identifier
- 991022202122704721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Nutrition & Dietetics
- Physiology
- Sport Sciences