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Journal article
Daily spirometry in an acute exacerbation of adult cystic fibrosis patients
Chronic respiratory disease, v 15(3), pp 258-264
Aug 2018
PMID: 29183160
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
To help answer the question of length of intravenous antibiotics during an acute exacerbation of cystic fibrosis (CF), we had subjects to follow daily home spirometry while on intravenous antibiotics. CF patients, 18 and older, with an acute exacerbation requiring intravenous antibiotics had a daily FEV1. The average time to a 10% increase over their initial sick FEV1 was calculated, as well as the time to a new baseline. A total of 25 subjects completed the study. Ten of the 25 subjects did not have a sustainable 10% increase in FEV1. Of the 15 subjects with a sustainable 10% increase in FEV1, it took 5.2 days (±4.5) after day 1, while a new baseline was achieved on average at 6.6 days (±4.8) after day 1. Given the wide range of time to a 10% improvement and new baseline, it is recommended there should be flexibility in length of intravenous antibiotics in CF, not by a preset number.
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Details
- Title
- Daily spirometry in an acute exacerbation of adult cystic fibrosis patients
- Creators
- Michael J Stephen - Drexel UniversityAlex Long - Drexel UniversityChad Bonsall - University of PennsylvaniaJeffrey B Hoag - Drexel UniversitySmita Shah - Saint Barnabas Medical CenterDorothy Bisberg - Saint Barnabas Medical CenterDouglas Holsclaw - University of PennsylvaniaLaurie Varlotta - 5 St Chrisophter's Hospital for Children, Philadelphia, PA, USA.Stan Fiel - 6 Atlantic Health System, Morristown, NJ, USADoantrang Du - Monmouth Medical CenterRobert Zanni - Monmouth Medical CenterDenis Hadjiliadis - University of Pennsylvania
- Publication Details
- Chronic respiratory disease, v 15(3), pp 258-264
- Publisher
- Sage
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Pediatrics; Pulmonary, Critical Care, and Sleep (Medicine)
- Web of Science ID
- WOS:000441030300004
- Scopus ID
- 2-s2.0-85051277859
- Other Identifier
- 991019168335404721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Respiratory System