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Deep brain stimulation for obesity: past, present, and future targets
Journal article   Open access   Peer reviewed

Deep brain stimulation for obesity: past, present, and future targets

Derrick A Dupré, Nestor Tomycz, Michael Y Oh and Donald Whiting
Neurosurgical focus, v 38(6), pp E7-E7
01 Jun 2015
PMID: 26030707
url
https://doi.org/10.3171/2015.3.FOCUS1542View
Published, Version of Record (VoR) Open

Abstract

Brain - anatomy & histology Brain - physiology Deep Brain Stimulation - history Deep Brain Stimulation - methods Deep Brain Stimulation - trends History, 20th Century History, 21st Century Humans Obesity - therapy
The authors review the history of deep brain stimulation (DBS) in patients for treating obesity, describe current DBS targets in the brain, and discuss potential DBS targets and nontraditional stimulation parameters that may improve the effectiveness of DBS for ameliorating obesity. Deep brain stimulation for treating obesity has been performed both in animals and in humans with intriguing preliminary results. The brain is an attractive target for addressing obesity because modulating brain activity may permit influencing both sides of the energy equation--caloric intake and energy expenditure.

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18 citations in Scopus

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Web of Science research areas
Clinical Neurology
Surgery
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