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Deep brain stimulation of the globus pallidus suppresses post-traumatic dystonic tremor
Journal article   Peer reviewed

Deep brain stimulation of the globus pallidus suppresses post-traumatic dystonic tremor

Karen S Carvalho, Vishad V Sukul, Markus J Bookland, Steven A Koch and Patrick J Connolly
Journal of clinical neuroscience, v 21(1), pp 153-155
01 Jan 2014
PMID: 23896546

Abstract

Adolescent Brain Injuries - complications Deep Brain Stimulation - methods Dystonic Disorders - etiology Dystonic Disorders - therapy Globus Pallidus - physiopathology Humans Male Tremor - etiology Tremor - therapy
Dystonic tremor is an unusual movement disorder that is highly disabling and difficult to treat medically. We describe an 18-year-old patient with dystonic tremor whose medical treatment failed, and was considered for surgery. The patient had a long-standing dystonic tremor and was recommended for globus pallidus (GP) deep brain stimulation. At 2 year follow-up, we observed substantial tremor suppression and best clinical effect with contact three, which, radiographically, is located in the internal globus pallidus/external globus pallidus transition area. The stimulation was more rostral than expected. We conclude that the GP is a potentially useful therapeutic target for dystonic tremor.

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Clinical Neurology
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