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Accepted (AM)Open Access (License Unspecified), Open
Journal article
Defining gaps in pre-exposure prophylaxis delivery for pregnant and post-partum women in high-burden settings using an implementation science framework
The lancet HIV, v 7(8), pp e582-e592
Aug 2020
PMID: 32763221
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Pregnancy is a high-risk period for HIV acquisition in African women, and pregnant women who become acutely infected with HIV account for up to a third of vertical HIV transmission cases in African settings. To protect women and eliminate vertical transmission, WHO recommends offering oral pre-exposure prophylaxis (PrEP) based on tenofovir to HIV-negative pregnant and post-partum women with a substantial risk of HIV acquisition. PrEP implementation for pregnant and post-partum women lags behind implementation for other high-risk populations. Unique considerations for PrEP implementation arise during pregnancy and post partum, including the integration of provider training with clinical delivery and monitoring of PrEP exposure and outcomes within existing maternal health systems, yet scarce implementation data are available to generate evidence in this context.
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Details
- Title
- Defining gaps in pre-exposure prophylaxis delivery for pregnant and post-partum women in high-burden settings using an implementation science framework
- Creators
- Jillian Pintye - University of WashingtonDvora L Joseph DaveyAnjuli D Wagner - University of WashingtonGrace John-Stewart - University of WashingtonRachel Baggaley - World Health OrganizationLinda-Gail Bekker - Desmond Tutu HIV FoundationConnie Celum - University of WashingtonBenjamin H Chi - University of North Carolina at Chapel HillThomas J Coates - University of California, Los AngelesAllison K Groves - Drexel UniversityJessica E Haberer - Massachusetts General HospitalRenee Heffron - University of WashingtonJohn Kinuthia - Kenyatta National HospitalLynn T Matthews - University of Alabama at BirminghamJames A McIntyre - Anova Health InstituteDhayendre Moodley - University of KwaZulu-NatalLynne M Mofenson - Elizabeth Glaser Pediatric AIDS FoundationNelly Mugo - Kenya Medical Research InstituteAndrew Mujugira - Makerere UniversityLandon Myer - University of Cape TownSteven Shoptaw - University of California, Los AngelesLynda Stranix-Chibanda - University of ZimbabweJared M Baeten - University of WashingtonPrEP in Pregnancy Working Group
- Publication Details
- The lancet HIV, v 7(8), pp e582-e592
- Publisher
- Elsevier
- Grant note
- K24 AI120796 / NIAID NIH HHS R01 HD094630 / NICHD NIH HHS R01 AI125498 / NIAID NIH HHS R01 HD100201 / NICHD NIH HHS L30 AI140785 / NIAID NIH HHS K01 MH121124 / NIMH NIH HHS R01 AI131060 / NIAID NIH HHS R01 MH116771 / NIMH NIH HHS R01 MH095507 / NIMH NIH HHS P30 AI027757 / NIAID NIH HHS 001 / World Health Organization K01 TW011187 / FIC NIH HHS
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Community Health and Prevention
- Web of Science ID
- WOS:000555999600015
- Scopus ID
- 2-s2.0-85088948124
- Other Identifier
- 991019168810504721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Immunology
- Infectious Diseases