Journal article
Delayed Brain Injury after Head Trauma
Neurosurgery, v 30(2), pp 160-165
01 Feb 1992
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Abstract
<p>We reviewed the records of 253 patients with head injury who required serial computed tomographic (CT) scans; 123 (48.6%) developed delayed brain injury as evidenced by new or progressive lesions after a CT scan. An abnormality in the prothrombin time, partial thromboplastin time, or platelet count at admission was present in 55% of the patients who showed evidence of delayed injury, and only 9% of those whose subsequent CT scans were unchanged or improved from the time of admission (P < 0.00 1). Among patients developing delayed injury, mean prothrombin time at admission was significantly longer (1 4.6 vs. 12.6 s, P < 0.00 1) and partial thromboplastin time was significantly longer (36.9 vs. 29.2 s, P < 0.001) than patients who did not have delayed injury. If coagulation studies at admission were normal, a patient with head injury had a 3 1 % risk of developing delayed insults. This risk rose to almost 85% if at least one clotting test at admission was abnormal (P < 0.001). We conclude that clotting studies at admission are of value in predicting the occurrence of delayed injury. If coagulopathy is discovered in the patient with head injury early follow-up CT scanning is advocated to discover progressive and new intracranial lesions that are likely to occur.</p>
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Details
- Title
- Delayed Brain Injury after Head Trauma
- Creators
- Sherman C. Stein - University Medical CenterGary S. Young - Cooper HospitalRaymond C. Talucci - University Hospital and ClinicsBarbara H. Greenbaum - University Medical CenterSteven E. Ross - University Medical Center
- Publication Details
- Neurosurgery, v 30(2), pp 160-165
- Publisher
- WILLIAMS & WILKINS; BALTIMORE
- Number of pages
- 6
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Surgery
- Web of Science ID
- WOS:A1992HA45400002
- Scopus ID
- 2-s2.0-0026574369
- Other Identifier
- 991021966871004721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Clinical Neurology
- Surgery