Journal article
Delayed Thrombosis or Stenosis Following Enterprise-Assisted Stent-Coiling: Is It Safe? Midterm Results of the Interstate Collaboration of Enterprise Stent Coiling
Neurosurgery, v 69(4), pp 908-913
01 Oct 2011
PMID: 21670718
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
BACKGROUND: Stent-assisted coiling of intracranial aneurysms with self-expanding stents has widened the applicability of neuroendovascular therapies to those aneurysms previously considered "uncoilable" because of poor morphology. The Enterprise Vascular Reconstruction Device and Delivery System (Cordis) has demonstrated promising initial short-term results. However, the rates of delayed in-stent stenosis or thrombosis are not known.
OBJECTIVE: To report midterm results of the Enterprise stent system.
METHODS: A 10-center registry was created to provide a large volume of data on the safety and efficacy of the Enterprise stent system. Pooled data were compiled for consecutive patients undergoing Enterprise stent-assisted coiling at each institution. Available follow-up data were evaluated for the incidence of in-stent stenosis, thrombosis, and aneurysm occlusion.
RESULTS: In total, 213 patients (176 females) with 219 aneurysms were treated with the Enterprise stent. One hundred ten patients had undergone delayed angiography (>= 30 days from stent placement, mean follow-up 174.6 days). Forty percent of patients demonstrated total occlusion with 88% having >= 90% aneurysm occlusion. Six percent of patients had delayed (>30 days) angiographic findings, of which 3% demonstrated significant (>= 50%) in-stent stenosis or occlusion. Seven delayed thrombotic events occurred (3%), along with 2 additional immediate periprocedural events. All 7 delayed events were concomitant to cessation of double-antiplatelet therapy.
CONCLUSION: Midterm occlusion rates are excellent, and stenosis and thrombosis rates are comparable to other available neurovascular stents. Interruption of antiplatelet therapy appears to be a factor in those developing delayed stenosis or thrombosis.
Metrics
5 Record Views
Details
- Title
- Delayed Thrombosis or Stenosis Following Enterprise-Assisted Stent-Coiling: Is It Safe? Midterm Results of the Interstate Collaboration of Enterprise Stent Coiling
- Creators
- J. Mocco - University of FloridaKyle M. Fargen - University of FloridaFelipe C. Albuquerque - Barrow Neurological InstituteBernard R. Bendok - Northwestern UniversityAlan S. Boulos - Albany Medical Center HospitalJeffrey S. Carpenter - West Virginia UniversityDavid J. Fiorella - State University of New YorkBrian L. Hoh - University of FloridaJay U. Howington - Florida CollegeKenneth M. Liebman - Capital HealthSabareesh K. Natarajan - University at Buffalo, State University of New YorkAnsaar T. Rai - West Virginia UniversityRafael Rodriguez-Mercado - Albany Medical Center HospitalAdnan H. Siddiqui - University at Buffalo, State University of New YorkKenneth V. Snyder - University at Buffalo, State University of New YorkErol Veznedaroglu - Capital HealthL. Nelson Hopkins - University at Buffalo, State University of New YorkElad I. Levy - University at Buffalo, State University of New York
- Publication Details
- Neurosurgery, v 69(4), pp 908-913
- Publisher
- Oxford Univ Press
- Number of pages
- 6
- Grant note
- Microvention Micrus Endovascular NIH; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA Codman Neurovascular Toshiba Boston Scientific Corp.; Boston Scientific University at Buffalo Boston Scientific Corp; Boston Scientific
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Neurology; Neurosurgery
- Web of Science ID
- WOS:000294684600065
- Scopus ID
- 2-s2.0-80053638259
- Other Identifier
- 991021933313604721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Clinical Neurology
- Surgery