Journal article
Delphi consensus-based recommendations of tools and outcomes for the assessment of radiation dermatitis severity
Radiotherapy and oncology, v 206, 110846
01 May 2025
PMID: 40086472
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Introduction: Acute radiation dermatitis (ARD) is a common side effect experienced during radiation therapy (RT) for cancer. Published clinical trials for ARD use a myriad of assessment tools and outcomes to measure ARD severity, which limits the comparability of clinical trial results. Our study utilized a modified Delphi consensus survey to gather expert opinions on commonly used tools for ARD severity. Materials and methods: Thirty experts were invited to participate in a two-round Delphi consensus survey. Of these, 80 % (24/30) completed the first round; and 92 % (22/24) completed the second round. The Delphi process was conducted using the REDCap platform to systematically collect expert opinions on 32 assessment tools and 11 key outcomes pertinent to the severity of ARD. Assessment tools and outcomes that achieved a consensus of ≥ 70 % among the experts were subsequently recommended. Results: Expert recommendations included four tools (RTOG, CTCAE, RISRAS, and Skindex-16) and eight relevant outcomes (moist desquamation, pain, QoL, erythema, dry desquamation, pruritus/itching, necrosis/ulceration, and burning) for ARD severity assessment. Due to limited evidence, no biophysical parameters reached consensus. Further, experts suggested modifications to existing tools to improve measurement of ARD severity across all skin types. Conclusion: Our study was the first step in standardizing ARD severity assessment with expert consensus recommendation for four tools and eight relevant outcomes. However, modifications to existing tools are necessary to promote validation and accuracy across all skin types. Future efforts should create a new comprehensive ARD severity assessment tool to address deficiencies in existing tools.
Metrics
1 Record Views
Details
- Title
- Delphi consensus-based recommendations of tools and outcomes for the assessment of radiation dermatitis severity
- Creators
- S. Minhaj Rahman - University of RochesterPartha Patel - University of OttawaSamuel Finkelstein - Tel Aviv UniversityShing Fung Lee - National University of SingaporeHenry Wong - Department of Oncology, Princess Margaret Hospital, Hospital Authority, Hong KongAdrian Wai Chan - Hospital AuthorityElwyn Zhang - Sunnybrook Health Science CentreJennifer Yin Yee Kwan - University of TorontoPierluigi Bonomo - Azienda Ospedaliero-Universitaria CareggiRaymond J. Chan - Flinders UniversityCorina van den Hurk - Radboud University NijmegenEdward Chow - Sunnybrook Health Science CentreSuvam Banerjee - Burdwan Medical College & HospitalMichele Aquilano - Casa di Cura ColumbusMark Trombetta - Drexel UniversityTara Behroozian - McMaster UniversityJulie Ryan Wolf - University of Rochester
- Publication Details
- Radiotherapy and oncology, v 206, 110846
- Publisher
- Elsevier
- Grant note
- Raunvísindastofnun, Háskóli Íslands (501100020584) Multinational Association of Supportive Care in Cancer (100011011) University of Rochester (100008091) CTSA UL1 TR002001 / University of Rochester Clinical & Translational Science Institute UL1 TR002001 / Georgia Clinical and Translational Science Alliance (100016220)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Radiology (Radiologic Sciences)
- Web of Science ID
- WOS:001486751900001
- Scopus ID
- 2-s2.0-105000065254
- Other Identifier
- 991022197420404721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
Source: SDGs in the Output
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Oncology
- Radiology, Nuclear Medicine & Medical Imaging